Is it an issue that needs to be dealt with in the first place? Is a lost 182 worthy of spending national defense treasures? Even with malicious intent (which usually is not present in these TFR/airspace clowns), how much damage are they really going to cause?
A 172 crashed into a building in Tampa. Killed the pilot and burned some fancy fake leather office chairs, but that was about it. If Noble 12 had been in Tampa, would he have actually shot the 172 down before he crashed into the building? I don't believe he would have, so then why bother launching even a AT-6? Similarly with the GWB dude, is our kill chain going to actually make a cognizant choice, weighing the collateral damage of airplane parts raining on Manhattan, PID, and shoot him down before he crashes into something? I don't think so and I think we're wasting a lot of time pretending we have "active air defense."