It doesn't even take anything that drastic. My doc was going to put me on a statin. I told him no and began a diet and exercise routine that has dropped my blood pressure 20 points on the systolic side, and watched my weight drop about 15 pounds along with losing 3 inches on my waist. The cholesterol is down from a high of mid-200's to 150-175; the LDLs are down from over 160 to below 100.
I do know some guys who just have the wrong genes and they need the meds, but most people can get by with diet and exercise and live a long, healthy life without the statins. I have been told if I end up on a statin to take an OTC CoQ-10. It helps to balance out some of the ill effects of the statin. Of course, if a flyer you need to disclose to your flight doc.