11-401 has not such spouse restriction (since Space A is not a orientation flight).
However, many units have restrictions in the form of a SRF or a sup. Our unit, for instance, has a SRF that says we will not allow our spouses to fly Space A on a plane we are on if we are listed on the orders. Our SRF came about from the "one person ruins it for everyone" file.
Long story short, a few years back, an AC released 20 seats, thinking his wife and kids would make it. They didn't. He then reduced the number to 15, told his wife to stick around in the terminal after everyone had left, and then called back and increased the seats back to 20, allowing his family to make it on the plane since nearly everyone in front of them had left the terminal...expect for one old retiree who called BS when he saw they were related once they were on the plane.